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Toluene-4-sulfonic acid 4-[(4-{[4-({4-[(4-benzyloxycarbonylamino-butyl)-tert-butoxycarbonyl-amino]-butyl}-tert-butoxycarbonyl-amino)-butyl]-tert-butoxycarbonyl-amino}-butyl)-tert-butoxycarbonyl-amino]-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

191489-04-0

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191489-04-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 191489-04-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,4,8 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 191489-04:
(8*1)+(7*9)+(6*1)+(5*4)+(4*8)+(3*9)+(2*0)+(1*4)=160
160 % 10 = 0
So 191489-04-0 is a valid CAS Registry Number.

191489-04-0Downstream Products

191489-04-0Relevant academic research and scientific papers

A microgonotropen branched decaaza decabutylamine and its DNA and DNA/transcription factor interactions

Bruice, Thomas C.,Sengupta, Dipanjan,Blasko, Andrei,Chiang,Beerman

, p. 685 - 692 (1997)

The central pyrrole of a site-selective DNA minor groove binding tripyrrole peptide 1 has been attached to a branched decaaza decabutylamine via a -(CH2)3-NHCO-(CH2)3- linker to provide the decaaza-microgonotropen (8). The decaaza decabutylamine moiety of 8 was designed to have a much greater affinity to the phosphodiester linkages of the backbone of DNA. Employing Hoechst 33258 (Ht) as a fluorescent titrant, the equilibrium constants for the binding of 8 to the hexadecameric duplex d(GGCGCA3T3GGCGG)/d(CCGCCA3T3GCGCC) and to calf thymus DNA were determined. The log of the product of equilibrium constants (log K(L1)K(L2) for 1:1 and 1:2 complexes formation at A3T3 is 17 (35°C). Results of studies of the inhibition of the binding of several proteins to target DNA are discussed. Binding of the E2F1 transcription factor to its DNA target is 50% inhibited at ~2 nM concentration of 8.

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