191602-43-4

Basic information

• Product Name: 3-BroMo-4-isopropoxyaniline
• Synonyms: 3-BroMo-4-isopropoxyaniline
• CAS NO: 191602-43-4
• Molecular Formula: C₉H₁₂BrNO
• Molecular Weight: 230.10168
• Mol File: 191602-43-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BroMo-4-isopropoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-4-isopropoxyaniline(191602-43-4)
• EPA Substance Registry System: 3-BroMo-4-isopropoxyaniline(191602-43-4)

Safety Data

• Hazardous Substances Data: 191602-43-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-isopropoxyaniline is a chemical compound with the molecular formula C10H14BrNO. It is a derivative of aniline, containing a bromine atom and an isopropoxy group attached to the aromatic ring. This chemical is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also known for its application in organic and medicinal chemistry research. 3-Bromo-4-isopropoxyaniline is considered to be a hazardous chemical and should be handled with care, following proper safety protocols and regulations.

Upstream product

• 5847-59-6 2-bromo-4-nitrophenol 
• 191602-42-3 2-bromo-1-isopropoxy-4-nitrobenzene 

Downstream Products

• 921194-46-9 4-isopropoxy-3-vinylaniline 

Relevant articles and documents

BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF

β-Substituted β-amino acids, β-substituted β-amino acid derivatives, and β-substituted β-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres are selective LAT1/4F2hc substrates and exhibit rapid uptake and retention in tumors expressing the LAT1/4F2hc transporter. Methods of synthesizing the β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and methods of using the compounds for treating cancer are also disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs exhibit selective uptake in tumor cells expressing the LAT1/4F2hc transporter and accumulate in cancerous cells when administered to a subject in vivo. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres exhibit cytotoxicity toward several tumor types.

Substituted benzazoles and methods of their use as inhibitors of Raf kinase

New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.