191741-40-9Relevant academic research and scientific papers
Substituent-dependent asymmetric induction in the ring transformation of 2,3-dihydroimidazo[2,1-a]phthalazin-4-ium-6-olates effected by acetic and propionic anhydrides
Szabo, Andras,Csampai, Antal,Koermendy, Karoly,Boecskei, Zsolt
, p. 7021 - 7034 (2007/10/03)
On the effect of acetic and propionic anhydrides 2,3-dihydroimidazo[2,1-a]phthalazin-4-ium-6-olates (1c-j) underwent ring transformation (1→7.8). Alternative mechanisms are applied to reason the characteristic substituent-dependent asymmetric induction observed for the transformations of the 2-monosubstituted precursors. The structures of products were determined by IR. MS. 1H- and 13C-NMR (1D- and 2D) measurements supported by single crystal X-ray analysis.
