19177-36-7 Usage
Chemical class
Indole amines
Structure
A heterocyclic compound containing a benzene ring fused to a five-membered nitrogen-containing ring
Substitution
Contains a substituted amine group
Attached groups
A 4-methoxyphenyl and a 2-phenyl group attached to the nitrogen atom
Biological activities
Possesses anti-inflammatory, antioxidant, and anti-cancer properties
Research significance
Important molecules for research in drug development and medicinal chemistry
Structural diversity
Exhibits a wide range of structural variations, which contributes to their diverse biological activities
Applications
Potential use in the development of new drugs targeting various diseases and conditions
Synthesis
Can be synthesized through various chemical reactions, such as the Fischer indole synthesis or the Bischler-Napieralski reaction
Stability
May be sensitive to certain conditions, such as light, heat, or moisture, and should be stored appropriately to maintain its integrity
Check Digit Verification of cas no
The CAS Registry Mumber 19177-36-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,7 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19177-36:
(7*1)+(6*9)+(5*1)+(4*7)+(3*7)+(2*3)+(1*6)=127
127 % 10 = 7
So 19177-36-7 is a valid CAS Registry Number.
19177-36-7Relevant academic research and scientific papers
Electro-oxidative C-H amination of heteroarenes with aniline derivativesviaradical-radical cross coupling
Feng, Pengju,Hu, Shiyu,Ma, Guojian,Peng, Xichao,Ruan, Zhixiong,Wu, Yan,Zhao, Junhao
, p. 8853 - 8858 (2021/11/23)
The selective synthesis of C-2/C-3 aminated five-membered heteroarenes incorporated various functionalities with aniline derivatives in a sustainable way remains an unmet challenge. This protocol presents a practical protocol for the C-H amination of heteroarenesviaan electro-oxidative cross coupling process. This electrosynthetic approach enables a facile access to a wide variety of synthetically useful hetero-arene derivatives, tolerates a wide range of functional groups, and is amenable to gram scale synthesis. In addition, a preliminary mechanistic study reveals that a radical cross coupling process between the N-centered radical and indole radical cation may be involved for this amination reaction.
