191861-17-3

Basic information

• Product Name: 9-fluoro-1,7-phenanthroline
• Synonyms: 1,7-phenanthroline, 9-fluoro-; 9-Fluoro-1,7-phenanthroline
• CAS NO: 191861-17-3
• Molecular Formula: C₁₂H₇FN₂
• Molecular Weight: 198.1958
• Mol File: 191861-17-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 368.4°C at 760 mmHg
• Flash Point: 176.6°C
• Density: 1.336g/cm³
• Vapor Pressure: 2.7E-05mmHg at 25°C
• Refractive Index: 1.712
• CAS DataBase Reference: 9-fluoro-1,7-phenanthroline(CAS DataBase Reference)
• NIST Chemistry Reference: 9-fluoro-1,7-phenanthroline(191861-17-3)
• EPA Substance Registry System: 9-fluoro-1,7-phenanthroline(191861-17-3)

Safety Data

• Hazardous Substances Data: 191861-17-3(Hazardous Substances Data)

Upstream product

• 56-81-5 glycerol 
• 155014-05-4 3-fluoroquinolin-5-amine 
• 191861-20-8 3-fluoro-5-nitroquinoline 
• 396-31-6 3-fluoroquinoline 

Relevant articles and documents

Dual stimulatory and inhibitory effects of fluorine-substitution on mutagenicity: An extension of the enamine epoxide theory for activation of the quinoline nucleus

Nineteen mono- and di-fluorinated derivatives of quinoline, 1,7- phenanthroline, 1,10-phenanthroline, benzo-[h]quinoline, and benzo[f]quinoline were subjected to analysis of their structure-mutagenicity relationships. For this purpose, six new fluorinated derivatives were synthesized. The results support that the enamine epoxide structure of the pyridine moiety, as well as the bay-region epoxide structure, is responsible for mutagenicity. Formation of K-region epoxides might involve a detoxification process rather than mutagenic activation.