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1-[4-(AMINOMETHYL)PHENYL]-N-METHYLMETHANESULFONAMIDE, also known as N-Methylmethanesulfonamide, is an organic sulfonamide compound with the molecular formula C9H13N3O2S. It possesses potential antineoplastic and antiangiogenic activities and is being investigated for its potential use in the treatment of various types of cancer, including solid tumors and hematological malignancies. 1-[4-(AMINOMETHYL)PHENYL]-N-METHYLMETHANESULFONAMIDE works by inhibiting the enzyme carbonic anhydrase, which plays a role in the regulation of pH in various tissues. Its potential efficacy and relatively low toxicity make it of interest in the field of cancer research.

191868-24-3

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191868-24-3 Usage

Uses

Used in Oncology:
1-[4-(AMINOMETHYL)PHENYL]-N-METHYLMETHANESULFONAMIDE is used as an antineoplastic agent for its potential to treat various types of cancer, including solid tumors and hematological malignancies. It targets the inhibition of carbonic anhydrase, which is involved in pH regulation in tissues, thereby affecting the tumor microenvironment and potentially limiting cancer progression.
Used in Cancer Research:
In the field of cancer research, 1-[4-(AMINOMETHYL)PHENYL]-N-METHYLMETHANESULFONAMIDE is used as a subject of investigation for its potential efficacy in treating cancer. Its relatively low toxicity compared to other antineoplastic agents makes it a promising candidate for further study and development.
Used in Drug Development:
1-[4-(AMINOMETHYL)PHENYL]-N-METHYLMETHANESULFONAMIDE is utilized in drug development as a potential lead compound for the creation of new cancer therapeutics. Its mechanism of action through carbonic anhydrase inhibition offers a unique approach to cancer treatment, and ongoing research aims to optimize its properties for clinical use.

Check Digit Verification of cas no

The CAS Registry Mumber 191868-24-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,8,6 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 191868-24:
(8*1)+(7*9)+(6*1)+(5*8)+(4*6)+(3*8)+(2*2)+(1*4)=173
173 % 10 = 3
So 191868-24-3 is a valid CAS Registry Number.

191868-24-3Relevant academic research and scientific papers

Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them

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, (2008/06/13)

NPY-antagonistic compounds of the formula STR1 Exemplary are: (A) (R)-N-[[4-(Aminocarbonylaminomethyl)phenyl]methyl]-N 2-bis(4-hydroxyphenyl)acetyl]-argininamide-trifluoracetate;(B) (R)-N-[[4-(Aminocarbonylaminomethyl)phenyl]methyl]-N 2-[bis(4-chlorphenyl)acetyl]-argininamide-trifluoracetate;(C) (R)-N-[[4-Aminocarbonylaminomethyl)phenyl]methyl]-N 2-(diphenylacetyl)-argininamide-trifluoracetate;(D) (R)-N 2-(Diphenylacetyl)-N-[[4-(ethoxycarbonylmethylamino-carbonylaminomethyl) phenyl]methyl]-argininamide-trifluoroacetate;(E) (R,S)-N 5-(Aminoiminomethyl)-N 2-(diphenylacetyl)-N-[(4-hy-droxyphenyl)methyl]-N 5-methyl-ornithinamide-hydrochloride; (F) (R)-N-[[4-(Aminocarbonylmethyl)phenyl]methyl]-N 2-(diphenyl-acetyl)-argininamide-diacetate;(G) (R)-N. sup. 2-(Diphenylacetyl)-N-[[4-(ethylaminocarbonylamino-methyl)-phenyl]methyl]-argininamide-bis-(trifluoroacetate); and,(H) (R)-N. sup.2-(Diphenylacetyl)-N-[[4-(ethoxycarbonylamino-carbonylaminomethyl) phenyl]methyl]-argininamide-trifluoroacetate.

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