191935-18-9

Upstream product

• 263711-17-7 (2S,3R)-4-benzyloxy-2,3-(dimethylmethylenedioxy)butyric acid 
• 871514-33-9 S-methyl (2S,3R)-4-benzyloxy-2,3-(dimethylmethylenedioxy)butanethioate 
• 81801-09-4 4-O-benzyl-2,3-O-isopropylidene-D-threose 
• 871514-57-7 ethyl [2S,2(1R,2S),3S,4R]-5-benzyloxy-2-[1,2-(diethylmethylenedioxy)-3-[(2-methoxyethoxy)methoxy]propyl]-3,4-(dimethylmethylenedioxy)-2-hydroxy-3-(methylthio)carbonylpentanoate 
• 191934-88-0 (R,Z)-4-(benzyloxy)methyl-5-[methylthio(trimethylsilyloxy)methylene]-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 871514-63-5 ethyl [2S,2(1R,2S),3S,4R]-5-benzyloxy-2-[3-benzyloxy-1,2-(diethylmethylenedioxy)propyl]-3,4-(dimethylmethylenedioxy)-2-hydroxy-3-(methoxycarbonyl)pentanoate 
• 871514-62-4 ethyl [3S,3(1R,2S),4S,8R]-3-[3-benzyloxy-1,2-(diethylmethylenedioxy)propyl]-8-(benzyloxymethyl)-6,6-dimethyl-1-oxo-2,5,7-trioxaspiro[3.4]octane-3-carboxylate 

Relevant academic research and scientific papers

Total synthesis of zaragozic acid C by an aldol-based strategy

A total synthesis of zaragozic acid C by a convergent strategy is described in which the key features include (1) the simultaneous creation of the C4 and C5 quaternary stereogenic centers by a Sn(OTf)2-promoted aldol coupling reaction between a

Total synthesis of the squalene synthase inhibitor zaragozic acid C

The total synthesis of zaragozic acid C has been achieved by a convergent strategy, wherein the key feature of the construction of 2,8-dioxabicyclo[3.2.1]octane core structure is a simultaneous creation of the C4 and C5 quaternary carbon centers by Sn(OTf