191935-34-9

Upstream product

• 191935-33-8 3-ethyl 1,2-dimethyl (1S,2S,3R,4R,5R,10R,11R)-10-benzyloxy-4,5-(diethylmethylenedioxy)-1,2-(dimethylmethylenedioxy)-11-methyl-6-oxo-12-phenyl-3-(trimethylsilyloxy)dodecane-1,2,3-tricarboxylate 
• 191935-30-5 3-ethyl 1,2-dimethyl (1S,2S,3R,4R,5R)-4,5-(diethylmethylenedioxy)-1,2-(dimethylmethylenedioxy)-5-formyl-3-(trimethylsilyloxy)pentane-1,2,3-tricarboxylate 
• 191935-29-2 3-ethyl 1,2-dimethyl (1S,2S,3R,4R,5S)-4,5-(diethylmethylenedioxy)-1,2-(dimethylmethylenedioxy)-6-hydroxy-3-(trimethylsilyloxy)hexane-1,2,3-tricarboxylate 
• 191935-28-1 3-ethyl 1,2-dimethyl (1S,2S,3R,4R,5S)-4,5-(diethylmethylenedioxy)-1,2-(dimethylmethylenedioxy)-3,6-dihydroxyhexane-1,2,3-tricarboxylate 
• 871514-33-9 S-methyl (2S,3R)-4-benzyloxy-2,3-(dimethylmethylenedioxy)butanethioate 
• 81801-09-4 4-O-benzyl-2,3-O-isopropylidene-D-threose 
• 871514-76-0 (4S,5S)-4-{(R)-[(4R,5S)-5-((5R,6R)-5-Benzyloxy-1-hydroxy-6-methyl-7-phenyl-hept-2-ynyl)-2,2-diethyl-[1,3]dioxolan-4-yl]-ethoxycarbonyl-trimethylsilanyloxy-methyl}-2,2-dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid dimethyl ester 
• 191935-25-8 ethyl [2R,2(1R,2S),3S,4R]-5-benzyloxy-2-[1,2-(diethylmethylenedioxy)-3-[(2-methoxyethoxy)methoxy]propyl]-3,4-(dimethylmethylenedioxy)-2-hydroxy-3-(methylthio)carbonylpentanoate 
• 871514-57-7 ethyl [2S,2(1R,2S),3S,4R]-5-benzyloxy-2-[1,2-(diethylmethylenedioxy)-3-[(2-methoxyethoxy)methoxy]propyl]-3,4-(dimethylmethylenedioxy)-2-hydroxy-3-(methylthio)carbonylpentanoate 
• 191935-26-9 ethyl [2R,2(1R,2S),3S,4R]-5-benzyloxy-2-[1,2-(diethylmethylenedioxy)-3-[(2-methoxyethoxy)methoxy]propyl]-3,4-(dimethylmethylenedioxy)-2-hydroxy-3-(methoxycarbonyl)pentanoate 
• 871514-66-8 (4S,5S)-4-[(R)-((4R,5S)-2,2-Diethyl-5-trimethylsilanyloxymethyl-[1,3]dioxolan-4-yl)-ethoxycarbonyl-trimethylsilanyloxy-methyl]-2,2-dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid dimethyl ester 
• 871514-74-8 (4S,5S)-4-{(R)-[(4R,5S)-2,2-Diethyl-5-(2-methoxy-ethoxymethoxymethyl)-[1,3]dioxolan-4-yl]-ethoxycarbonyl-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid 4-methyl ester 
• 191935-27-0 3-ethyl 1,2-dimethyl (1S,2S,3R,4R,5S)-4,5-(diethylmethylenedioxy)-1,2-(dimethylmethylenedioxy)-3-hydroxy-6-[(2-methoxyethoxy)methoxy]hexane-1,2,3-tricarboxylate 
• 871514-72-6 (4S,5R)-4-{(R)-[(4R,5S)-2,2-Diethyl-5-(2-methoxy-ethoxymethoxymethyl)-[1,3]dioxolan-4-yl]-ethoxycarbonyl-hydroxy-methyl}-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester 

Downstream Products

• 191935-35-0 tri(tert-butyl) [1S,1(4R,5R),3S,4S,5R,6R,7R]-1-(4-benzyloxy-5-methyl-6-phenylhexyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 191935-36-1 tri(tert-butyl) [1S,1(4R,5R),3S,4S,5R,6R,7R]-4,6,7-trihydroxy-1-(4-hydroxy-5-methyl-6-phenylhexyl)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 171190-05-9 tri(tert-butyl) [1S,1(4R,5R),3S,4S,5R,6R,6(4E,6R),7R]-1-(4-acetoxy-5-methyl-6-phenylhexyl)-7-(tert-butoxycarbonyloxy)-4-hydroxy-6-(6-methyl-9-phenyl-4-nonenoyl)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 171190-04-8 tri(tert-butyl) [1S,1(4R,5R),3S,4S,5R,6R,7R]-1-(4-acetoxy-5-methyl-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-4,6-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 164215-53-6 tri(tert-butyl) [1S,1(4R,5R),3S,4S,5R,6R,7R]-6,7-diacetoxy-1-(4-acetoxy-5-methyl-6-phenylhexyl)-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 146389-62-0 (+)-zaragozic acid 
• 156661-55-1 (1S,3S,4S,5R,6R,7R,4'R,5'R)-1-[4'-acetoxy-5'-methyl-6'-phenylhex-1'-yl]-3,4,5-tris(2,2-dimethylpropionyl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane 

Relevant academic research and scientific papers

Total synthesis of zaragozic acid C by an aldol-based strategy

A total synthesis of zaragozic acid C by a convergent strategy is described in which the key features include (1) the simultaneous creation of the C4 and C5 quaternary stereogenic centers by a Sn(OTf)2-promoted aldol coupling reaction between a

Total synthesis of the squalene synthase inhibitor zaragozic acid C

The total synthesis of zaragozic acid C has been achieved by a convergent strategy, wherein the key feature of the construction of 2,8-dioxabicyclo[3.2.1]octane core structure is a simultaneous creation of the C4 and C5 quaternary carbon centers by Sn(OTf