1919853-46-5 Usage
General Description
PTP1B-IN-2 is a chemical compound that has been developed as an inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B is an enzyme that plays a role in the regulation of insulin and leptin signaling, making it a potential target for the treatment of obesity and diabetes. PTP1B-IN-2 has been shown to inhibit PTP1B activity in vitro and in cellular assays, suggesting its potential use as a therapeutic agent for metabolic disorders. Further studies are needed to evaluate its efficacy and safety for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 1919853-46-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,1,9,8,5 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1919853-46:
(9*1)+(8*9)+(7*1)+(6*9)+(5*8)+(4*5)+(3*3)+(2*4)+(1*6)=225
225 % 10 = 5
So 1919853-46-5 is a valid CAS Registry Number.
1919853-46-5Relevant articles and documents
Novel substituted sulfamide compound, preparation method and application thereof as PTP1B inhibitor
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Paragraph 0019; 0027, (2017/06/28)
The invention relates to a novel substituted sulfamide compound of a structure of a formula I as shown in the description, a pharmaceutically acceptable salt of the novel substituted sulfamide compound, a preparation method, and relates to a medicinal composition comprising the compound of the formula I or a pharmaceutically acceptable salt of the compound. The compound of the formula I or the pharmaceutically acceptable salt of the compound has activity of inhibiting protein tyrosine phosphatase 1B (PTP1B), so that the compound or the pharmaceutically acceptable salt of the compound has an application of preparing a medicine for preventing/treating symptoms or diseases such as hyperglycemia and type-2 diabetes.
