191990-63-3Relevant academic research and scientific papers
Tetrahydropyrimidine derivatives as efficient organic reductants for transfer hydrogenation
Zhang, Yongbin,Zhou, Guofu,Guo, Wei
experimental part, p. 1541 - 1548 (2009/12/24)
Two six-membered heterocyclic organic reductants, 1-acetyl-2,3-dimethyltetrahydropyrimidine (ADMP) and 1-tosyl-2,3-dimethyltetrahydro-pyrimidine (TDMP), were designed and synthesized for transfer hydrogenation. It was shown that both the two reductants could directly reduce a variety of aldehydes and imines to the corresponding saturated products in good yields.
Selective Synthesis of Polyamine Derivatives: Efficient Derivatization of the Secondary Amino Group of N-Monosubstituted 1,3-Diamines
Jentgens, Christian,Hofmann, Richard,Guggisberg, Armin,Bienz, Stefan,Hesse, Manfred
, p. 966 - 978 (2007/10/03)
N-Monosubstituted 1,3-diamines were selectively functionalized at the secondary N-atom via 2-Ph-substituted hexahydropyrimidine intermediates. Reaction of the diamines with benzaldehyde, followed by treatment with an electrophile and hydrolysis, provided
