192068-97-6Relevant academic research and scientific papers
Synthesis and reactions of 1,2-disubstituted methylenecyclopropanes prepared via intramolecular cyclopropanation of allenic diazoacetates
Lautens, Mark,Meyer, Christophe,Van Oeveren, Arjan
, p. 3833 - 3836 (1997)
Diazoacetates derived from α- or β-allenic alcohols, prepared using the glyoxylic acid chloride p-toluenesulfonylhydrazone method, undergo regioselective intramolecular cyclopropanation in the presence of a copper (II) catalyst in refluxing toluene, leading to synthetically useful di- or trisubstituted methylenecyclopropyl lactones. The diastereoselectivity of the process has been studied.
