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CAS

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192069-69-5

4-(4-Methyl-piperazine-1-carbonyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 192069-69-5 Structure

  • Basic information

    1. Product Name: 4-(4-Methyl-piperazine-1-carbonyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester
    2. Synonyms:
    3. CAS NO:192069-69-5
    4. Molecular Formula:
    5. Molecular Weight: 387.522
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 192069-69-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(4-Methyl-piperazine-1-carbonyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(4-Methyl-piperazine-1-carbonyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(192069-69-5)
    11. EPA Substance Registry System: 4-(4-Methyl-piperazine-1-carbonyl)-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester(192069-69-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 192069-69-5(Hazardous Substances Data)

192069-69-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 192069-69-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,0,6 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 192069-69:
(8*1)+(7*9)+(6*2)+(5*0)+(4*6)+(3*9)+(2*6)+(1*9)=155
155 % 10 = 5
So 192069-69-5 is a valid CAS Registry Number.

192069-69-5Downstream Products

192069-69-5Relevant articles and documents

Synthesis and structure-activity relationships for a series of substituted pyrrolidine NK1/NK2 receptor antagonists

Burkholder, Timothy P.,Kudlacz, Elizabeth M.,Maynard, George D.,Liu, Xiao-Gao,Le, Tieu-Binh,Webster, Mark E.,Horgan, Stephen W.,Wenstrup, David L.,Freund, David W.,Boyer, Fred,Bratton, Larry,Gross, Raymond S.,Knippenberg, Robert W.,Logan, Deborah E.,Jones, Bryan K.,Chen, Teng-Man,Geary, Julie L.,Correll, Melinda A.,Poole, J. Chuck,Mandagere, Arun K.,Thompson, Thomas N.,Hwang, Kin-Kai

, p. 2531 - 2536 (2007/10/03)

We recently described the synthesis and characterization of MDL 105,212, a non peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors. Here we report the synthesis and structure-activity relationships for a series of analogs of MDL 105,212 with regards to: NK1 and NK2 receptor binding affinity, physical-chemical characterization; in vitro absorption potential; in vitro metabolic stability; and efficacy in a capsaicin-challenge conscious guinea pig model after oral administration.

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