192130-06-6

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-(2-Hydroxyethylamino)-pyridine is used as a key building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and pesticidal properties, contributing to advancements in medicine and agriculture.
Used in Corrosion Inhibition:
4-(2-Hydroxyethylamino)-pyridine is studied for its potential as a corrosion inhibitor for metal surfaces. Its ability to form protective films and reduce metal degradation makes it a promising candidate for use in various industrial applications, including oil and gas pipelines, automotive components, and construction materials, to enhance their durability and longevity.
Used in Chemistry and Materials Science Research:
As a versatile chemical intermediate, 4-(2-Hydroxyethylamino)-pyridine is utilized in various research applications within the fields of chemistry and materials science. Its unique structure and properties enable the exploration of new chemical reactions, synthesis methods, and material formulations, driving innovation and discovery in these scientific domains.

InChI:InChI=1/C7H10N2O/c10-6-5-9-7-1-3-8-4-2-7/h1-4,10H,5-6H2,(H,8,9)

Upstream product

• 626-61-9 4-Chloropyridine 
• 141-43-5 ethanolamine 

Downstream Products

• 22731-70-0 1-(4-bromophenyl)prop-2-en-1-one 
• 170434-10-3 4-bromo-1-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctyloxy)benzene 
• 238099-24-6 1-(4-bromophenyl)-2-ferrocenylacetylene 
• 403819-41-0 1-(1'-acetylferrocen-1-ylethynyl)-4-bromobenzene 
• 403819-27-2 1,4-bis-(1'-acetyl-1-ethynylferrocen-1-yl)-1,3-butadiyne 
• 690264-67-6 [2-(4-bromo-phenoxy)-ethyl]-pyridin-4-yl-amine 

Relevant academic research and scientific papers

SUBSTITUTED QUINAZOLINE DERIVATIVES AS DNA METHYLTRANSFERASE INHIBITORS

The present invention relates to compounds of the following formula (I) and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.

QUINAZOLINE DERIVATIVES AND THEIR USE AS DNA METHYLTRANSFERASE INHIBITORS

The present invention relates to compounds of the following formula (I): and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.

Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds

The present invention relates to alkyne compounds of general formula I wherein the groups and residues A, B, W, X, Y, Z, R1 and R2 have the meanings given in claim 1. The invention further relates to pharmaceutical compositions containing at least one alkyne according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.

Chemical compounds

The invention relates to quinazoline derivatives of the formula: [wherein: Y1represents —O—, —S—, —CH2—, —SO—, —SO2—, —NR5CO—, —CONR6—, —SO2NR7—, —NR8SO2— or —NR9— (wherein R5, R6, R8and R9each independently represents hydrogen, alkyl or alkoxyalkyl); R1represents hydrogen, hydroxy, halogeno, nitro, trifluoromethyl, cyano, alkyl, alkoxy, alkylthio, amino or alkylamino. R2represents hydrogen, hydroxy, halogeno, alkyl, alkoxy, trifluoromethyl, cyano, amino or nitro; m is an integer from 1 to 5; R3represents hydroxy, halogeno, alkyl, alkoxy, alkanoyloxy, trifluoromethyl, cyano, amino or nitro; R4represents a group which is or which contains an optionally substituted pyridone, phenyl or aromatic heterocyclic group] and salts thereof; processes for their preparation and pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.