192130-15-7Relevant academic research and scientific papers
Derivatives of 4-amino-pyridine as selective thrombin inhibitors
Von der Saal, Wolfgang,Kucznierz, Ralf,Leinert, Herbert,Engh, Richard A.
, p. 1283 - 1288 (2007/10/03)
During screening for novel thromin inhibitors it was discovered that the 4-aminopyridine derivative 1 inhibits human α-thrombin competitively and selectively. The 4-aminopyridine moiety itself is most likely the major determinant of the selectivity due to
