192133-09-8Relevant articles and documents
Efficient syntheses of L-ribose and 2-deoxy L-ribose from D-ribose and L-arabinose
Jung, Michael E.,Xu, Yue
, p. 4199 - 4202 (1997)
Interconversion of the ends of D-ribose 2 afforded in 6 steps and 45% overall yield L-ribose 1, from which 2-deoxy L-ribose 12 was easily prepared. In addition, the inexpensive L-arabinose 13 was also converted into 2-deoxy L-ribose 12 via a reductive radical rearrangement of the arabinopyranosyl bromide 14.
Synthesis and testing of new modified nucleosides
Jung, Michael E.,Nichols, Christopher J.,Kretschik, Oliver,Xu, Yue
, p. 541 - 546 (2007/10/03)
New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-c and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analogues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.