192189-15-4

Usage

Uses

Used in Organic Synthesis:
1-Boc-3-bromo-1H-pyrrolo[3,2-b]pyridine is used as a key intermediate for the synthesis of complex organic molecules. Its Boc group serves a protective role during reactions, ensuring the amine functionality remains intact until deprotected at a later stage, which is crucial for the successful synthesis of target compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Boc-3-bromo-1H-pyrrolo[3,2-b]pyridine is utilized as a building block for the development of pharmaceuticals. Its unique structure allows for the creation of novel drug candidates with potential therapeutic applications, contributing to the discovery of new treatments for various diseases.
Used in Drug Discovery:
1-Boc-3-bromo-1H-pyrrolo[3,2-b]pyridine is employed as a component in drug discovery processes. Its reactivity and structural attributes facilitate the design and synthesis of new chemical entities that can be evaluated for their pharmacological properties, leading to the identification of potential drug candidates.
Used in the Synthesis of Biologically Active Molecules:
1-Boc-3-broMo-1H-pyrrolo[3,2-b]pyridine is also used in the synthesis of biologically active molecules, where its specific structural features can impart desired biological activities. The incorporation of 1-Boc-3-bromo-1H-pyrrolo[3,2-b]pyridine into these molecules can lead to the development of new agents with significant impacts on biological systems and potential applications in therapeutics or diagnostics.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 23688-47-3 3-bromo-1H-pyrrolo[3,2-b]pyridine 
• 272-49-1 1H-pyrrolo[3,2-b]pyridine 

Relevant academic research and scientific papers

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

NOVEL CLOSTRIDIUM DIFFICILE TOXIN INHIBITORS

The present invention relates to benzodiazepine derivative compounds of formula (I), or pharmaceutically acceptable salts thereof. The present benzodiazepine compounds are useful Clostridium difficile inhibitors in the treatment of Clostridium difficile infection in humans. The present invention provides a pharmaceutical composition containing benzodiazepine compounds of formula (I) and a method of making as well as a method of using the same in treating patients infected with Clostridium difficile infection by administering the same. The compounds of the present invention may be used in combination with additional antibiotics or anti-toxin antibody drugs.

HETEROARYL SUBSTITUTED BENZOIC ACIDS AS RORGAMMAT INHIBITORS AND USES THEREOF

The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.

4-AZAINDOLE BISPHOSPHONATES

Novel 4-azaindole bisphosphonate compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating abnormal calcium and phosphate metabolism, including bone and joint diseases and other disorders.

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl- dipyridodiazepinones

Modification of the non-nucleoside inhibitor of HIV-1 reverse transcriptase nevirapine (Viramune) by incorporation of a 2-indolyl substituent confers activity against several mutant forms of the enzyme.