192223-36-2Relevant academic research and scientific papers
Aminoborohydrides. 6. Diastereoselective Reduction of the Carbon-Nitrogen Double Bond in Chiral Imines Using Lithium Diethylaminoborohydride and Lithium Diisopropylaminoborohydride.
Fuller, Joseph C.,Belisle, Christopher M.,Goralski, Christian T.,Singaram, Bakthan
, p. 5389 - 5392 (1994)
Lithium aminoborohydrides (LAB), obtained by the reaction of n-BuLi with amine-boranes, readily reduce imines to the corresponding secondary amines.Lithium diethylaminoborohydride and lithium diisopropylaminoborohydride reduc
Addition of organozincate reagents to imines derived from (S)-1-phenylethylamine and ethyl (S)-valinate-synthesis of (S)-1-(2-pyridyl)alkylamines
Alvaro, Giuseppe,Pacioni, Paolo,Savoia, Diego
, p. 726 - 731 (2007/10/03)
Triorganozincates were added to aliphatic aldimines derived from (S)-1-phenylethylamine and (S)-valine esters in the presence of boron trifluoride to give secondary amines with low diastereoselectivies. From mixed zincates, most alkyl groups (methyl, ethy
Asymmetric Catalyses, 14. Enantioselective Hydrosilylation of Prochiral Ketones with Rh- and Pt-Complexes of Optically Active N-Chelate Ligands
Brunner, Henri,Reiter, Barbara,Riepl, Georg
, p. 1330 - 1354 (2007/10/02)
N-chelate ligands with a lateral chiral center, which derive from optically active primary amines, amino acids, and amino acid derivatives, catalyze in Rh and Pt complexes the enantioselective hydrosilylation of acetophenone, benzyl methyl ketone, and tert-butyl methyl ketone with diphenyl- and 1-naphthylphenylsilane.The ketones are transformed into the corresponding silyl ethers which on hydrolysis yield the alcohols 1-phenylethanol, 1-phenyl-2-propanol and 3,3-dimethyl-2-butanol. 37 N ligands 1 - 37 with 2 (I) and K (XX) as well as 21 isolated complexes II - XIX and XXI - XXIII are tested.The best optical inductions exceed considerably those which were obtained with optically active phosphane containing catalysts used up to now.
