192226-08-7

Upstream product

• 192226-06-5 5-Acetoxy-4-nitro-7-(tetrahydro-pyran-2-yloxy)-heptanoic acid tert-butyl ester 
• 192226-05-4 5-Hydroxy-4-nitro-7-(tetrahydro-pyran-2-yloxy)-heptanoic acid tert-butyl ester 
• 110106-95-1 4-nitrobutanoic acid t-butyl ester 
• 192226-07-6 4-(2-tert-Butoxycarbonyl-ethyl)-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-1H-pyrrole-2-carboxylic acid benzyl ester 

Downstream Products

• 192226-09-8 4-(2-tert-Butoxycarbonyl-ethyl)-3-tert-butoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of immunocomponents for the measurement of lead (Pb) by fluorescence polarization immunoassay

Three novel haptens (5b, 9b, 11b) were synthesized from porphobilinogen (2) and conjugated to bovine serum albumin to afford immunogens (6, 10, 12). Five fluorescent tracers (14, 17, 19, 29, 32) were prepared from porphobilinogen (2), or haptens (9b, 11b, 20b) in >98% purity. The immunogens (6, 10, 12) were utilized for generation of polyclonal antibodies and the best tracer-antibody combination was selected to construct the calibration curve for the measurement of lead.