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17-Hydroxypregnane-3,11,20-trione, also known as 17-hydroxyprogesterone or 17-OH-progesterone, is a steroid hormone derived from pregnane. It is an important intermediate in the biosynthesis of other steroid hormones, such as cortisol, aldosterone, and testosterone. 17-hydroxypregnane-3,11,20-trione plays a crucial role in the regulation of various physiological processes, including the stress response, immune function, and reproductive system. In medical settings, 17-hydroxypregnane-3,11,20-trione is used as a diagnostic marker for adrenal gland disorders and congenital adrenal hyperplasia, as well as a precursor in the synthesis of certain pharmaceuticals. Its chemical structure consists of a pregnane nucleus with hydroxyl groups at the 3, 11, and 20 positions, and a ketone group at the 17 position.

1923-68-8

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1923-68-8 Usage

Type

Synthetic chemical compound

Potent anti-inflammatory

It has strong anti-inflammatory effects.

Immunosuppressive

It suppresses the immune system.

Derivative of

Natural steroid hormone progesterone

Usage

Commonly used in laboratory research to study the effects of glucocorticoid receptor agonists.

Inhibits production of pro-inflammatory cytokines

It stops the production of substances that cause inflammation.

Reduces inflammation in animal models

It has been tested in animals and shown to decrease inflammation.

Rheumatoid arthritis

It is being investigated for use in treating this autoimmune disease.

Asthma

It may be useful in managing this respiratory condition.

Allergic reactions

It could potentially help with treating severe allergic reactions.

Cancer Treatment Potential

It has shown promise as a potential treatment for certain types of cancer due to its ability to induce cell death in tumor cells.

Check Digit Verification of cas no

The CAS Registry Mumber 1923-68-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,2 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1923-68:
(6*1)+(5*9)+(4*2)+(3*3)+(2*6)+(1*8)=88
88 % 10 = 8
So 1923-68-8 is a valid CAS Registry Number.

1923-68-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S,9S,10S,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,11-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1923-68-8 SDS

1923-68-8Relevant academic research and scientific papers

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