192316-91-9

Upstream product

• 2096-10-8 adenosine-2-amine 
• 1462-37-9 bromoethyl-2-benzyl ether 
• 853748-72-8 2'-O-(2-benzyloxyethyl)-2-aminoadenosine 

Downstream Products

• 853748-74-0 3',5'-bis(tert-butyldimethylsilyl)-2'-O-(2-benzyloxyethyl)-N²-isobutyrylguanosine 
• 853748-84-2 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-(triphenylmethylthio)ethyl)-N²-isobutyrylguanosine 
• 853748-78-4 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-(trifluoroacetamido)ethyl)-N²-isobutyrylguanosine 
• 853748-82-0 2'-O-(2-(triphenylmethylthio)ethyl)-N²-isobutyrylguanosine 
• 853748-73-9 3',5',O⁶-tris(tert-butyldimethylsilyl)-2'-O-(2-benzyloxyethyl)guanosine 

Relevant academic research and scientific papers

Synthesis of amine- and thiol-modified nucleoside phosphoramidites for site-specific introduction of biophysical probes into RNA

For studies of RNA structure, folding, and catalysis, site-specific modifications are typically introduced by solid-phase synthesis of RNA oligonucleotides using nucleoside phosphoramidites. Here, we report the preparation of two complete series of RNA nu

Synthesis of guanosine analogs bearing pendant alkylthiol tethers

Synthesis of three guanosine monomers substituted with alkylthiol chains at either carbon-8 or the 2'-hydroxyl is described. The ready accessibility of these monomers will facilitate the use of disulfide cross-links to study the folding and dynamics of RN