192461-84-0Relevant academic research and scientific papers
Zinc-catalyzed enantioselective hydrosilylation of imines
Park, Bu-Mahn,Mun, Soungyun,Yun, Jaesook
, p. 1029 - 1032 (2007/10/03)
The highly enantioselective reduction of imines is achieved by employing chiral Zn/diamine catalysts. This new catalytic protocol offers attractive features such as use of a non-precious metal and an inexpensive silane, easy modification of chiral diamine
Enantioselective borohydride reduction catalyzed by optically active cobalt complexes
Yamada, Tohru,Nagata, Takushi,Sugi, Kiyoaki D.,Yorozu, Kiyotaka,Ikeno, Taketo,Ohtsuka, Yuhki,Miyazaki, Daichi,Mukaiyama, Teruaki
, p. 4485 - 4509 (2007/10/03)
The highly enantioselective borohydride reduction of aromatic ketones or imines to the corresponding alcohols was developed in the presence of a catalytic amount of an optically active cobalt(II) complex catalyst. This enantioselective reduction is carried out using a precisely premodified borohydride with alcohols such as tetrahydrofurfuryl alcohol, ethanol and methanol. High optical yields are obtained by choosing the appropriate alcohol as modifiers and a suitable β-ketoiminato ligand of the catalyst. The enantioselective borohydride reduction has been successfully applied to the preparation of optically active 1,3-diols, the stereoselective reduction of diacylferrocenes, and dynamic and/or kinetic resolution of 1,3-dicarbonyl compounds.
Enantioselective borohydride reduction of N-diphenylphosphinyl imines using optically active cobalt(II) complex catalysts
Sugi, Kiyoaki D.,Nagata, Takushi,Yamada, Tohru,Mukaiyama, Teruaki
, p. 493 - 494 (2007/10/03)
The enantioselective borohydride reduction using optically active cobalt(II) complex catalysts was successfully applied to various aryl N-diphenylphosphinyl imines, and the corresponding reduced products were obtained in good yields with high enantiomeric excesses (up to 99% ee). The optically active primary amines were obtained by the successive hydrolysis under mild conditions.
