19248-13-6

Usage

Uses

Used in Dye and Pigment Production:
N-(2-AMINOETHYL)-N-ETHYL-M-TOLUIDINE serves as a crucial component in the creation of dyes and pigments, providing the necessary characteristics for coloration across different products and materials.
Used in Pharmaceutical Manufacturing:
Within the pharmaceutical industry, N-(2-AMINOETHYL)-N-ETHYL-M-TOLUIDINE is utilized in the development and production of various medications, contributing to the formulation of active pharmaceutical ingredients or serving as a key intermediate in synthesis processes.
Used in Research Laboratories:
This chemical compound also plays a significant role in research settings, where it may be employed in experiments and studies aimed at understanding its properties, potential applications, and effects, including its carcinogenic nature and how to safely incorporate it into industrial and scientific applications.
Given the potential carcinogenic properties of N-(2-AMINOETHYL)-N-ETHYL-M-TOLUIDINE, it is imperative that industries and laboratories implement proper handling procedures and safety measures to protect workers and the environment from undue exposure.

InChI:InChI=1/C11H18N2/c1-3-13(8-7-12)11-6-4-5-10(2)9-11/h4-6,9H,3,7-8,12H2,1-2H3

Upstream product

• 151-56-4 ethyleneimine 
• 102-27-2 N-ethyl-m-toulidine 
• 2498-02-4 N-[2-(N-ethyl-m-toluidino)-ethyl]-phthalimide 
• 42816-34-2 N-Ethyl-N-(2-propionamidoethyl)-m-toluidine 
• 58861-74-8 2-bromoethylamine hydrochloride 
• 91-88-3 N-ethyl-N-(2-hydroxyethyl)-3-methylaniline 
• 22564-43-8 N-(2-chloro-ethyl)-N-ethyl-3-methyl-aniline 

Downstream Products

• 37717-68-3 N-[2-(N-ethyl-m-toluidino)-ethyl]-methanesulfonamide 
• 14118-02-6 N.N'Bis-<2-(N-aethyl-m-toluidino-aethyl)-dithiooxamid 
• 459429-39-1 SB 452533 
• 108623-11-6 N-Aethyl-N-(2-phenylcarbamoylaminoaethyl)-m-toluidin 
• 229627-08-1 3-[[2-(ethyl-m-tolyl-amino)-ethyl]-({2-[3-methoxy-4-(3-o-tolylureido)phenyl]-acetylamino}-acetyl)-amino]-propionic acid 
• 868593-15-1 N-{2-[ethyl(3-methylphenyl)amino]ethyl}-N'-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)urea 

Relevant academic research and scientific papers

Discovery of small molecule antagonists of TRPV1

Small molecule antagonists of the vanilloid receptor 1 (TRPV1, also known as VR1) are disclosed. Ureas such as 5 (SB-452533) were used to explore the structure activity relationship with several potent analogues identified. Pharmacological studies using electrophysiological and FLIPR Ca2+ based assays showed compound 5 was an antagonist versus capsaicin, noxious heat and acid mediated activation of TRPV1. Study of a quaternary salt of 5 supports a mode of action in which compounds from this series cause inhibition via an extracellularly accessible binding site on the TRPV1 receptor.

2-aminobenzoxazole derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminobenzoxazole derivative compounds of the following formula: wherein R1 to R4 and Z have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminobenzoxazole derivative compounds.

Nucleophilic Ring Opening of 2-Oxazolines with Amines: A Convenient Synthesis for Unsymmetrically Substituted Ethylenediamines

The reaction of 2-alkyl-2-oxazolines with alkyl- and arylamines was investigated.The acid-catalyzed nucleophilic ring opening of the 2-oxazolines yields N-(2-aminoethyl)carboxamides in good to excellent yields with secondary amines and hindered primary amines.The N-(2-aminoethyl)carboxamides were hydrolyzed under acidic or basic conditions to selectively yield unsymmetrically substituted ethylenediamines.