19250-17-0

Usage

InChI:InChI=1/C10H14O2/c1-10(2)6-3-4-7(9(11)12)8(10)5-6/h4,6,8H,3,5H2,1-2H3,(H,11,12)

Upstream product

• 564-94-3 6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carbaldehyde 
• 80-56-8 Pinene 
• 515-00-4 myrtenol 

Relevant academic research and scientific papers

Synthesis and Bioactivity of N-(4-(N′-Substituted Sulfamoyl)Phenyl)Myrtenamides Containing a Heterocycle

A series of N-(4-(N′-substituted sulfamoyl)phenyl)myrtenamides containing a heterocycle were designed and synthesized by a multiple-step procedure using α-pinene as starting material. All the synthesized compounds were characterized and analyzed by GC, HPLC, UV-vis, FTIR, NMR, GC-MS, and ESI-MS. The preliminary bioassay showed that, at 50 μg/mL, the target compounds exhibited a certain antifungal activity against the five tested fungi, in which compound 5f exhibited antifungal activity of 83.2% and 70.0% against Physalospora piricola and Alternaria solani, respectively. Moreover, compound 5d displayed herbicidal activity of 86.0% against the root of rape (Brassica campestris) at 100 μg/mL.

Synthesis method of myrtenyl dihydrazide compound with fungal inhibition activity

A synthesis method of a myrtenyl dihydrazide compound with fungal inhibition activity comprises the following steps of: firstly, selectively oxidizing alpha-pinene into myrtenyl, further oxidizing the myrtenyl into myrtenic acid, then reacting the myrtenic acid with thionyl chloride to obtain myrtenic acid acyl chloride, and finally, carrying out hydrazinolysis reaction with a series of substituted benzoyl hydrazine or 2-pyridine formyl hydrazine under an anhydrous condition, and synthesizing to obtain the myrtenyl dihydrazide compound. A bacteriostatic activity test shows that the myrtenyl dihydrazide compound has excellent broad-spectrum inhibitory activity on various plant pathogenic fungi, and can be used as a lead compound of a novel agricultural bactericide.

Synthesis of Myrtenal-Based Nanocellulose/Diacylhydrazine Complexes with Antifungal Activity for Plant Protection

In search of novel bioactive compounds with excellent and broad-spectrum antifungal activity and nanopesticides with sustained releasing property, a series of novel myrtenal-based diacylhydrazines were designed, synthesized, and characterized. The preliminary bioassay showed that myrtenal-based 2-picolinyl hydrazide exhibited better or comparable antifungal activity than that of the commercial fungicides boscalid and chlorothalonil against the tested fungi. Furthermore, myrtenal-based nanocellulose was designed as a nanopesticide carrier and prepared from two biomass materials, bleached bagasse pulp and turpentine oil. Drug-loading capacities (LCs) of these carriers and sustained releasing properties of corresponding complexes were also evaluated, and the results indicated that the esterification reaction in the different solvents would affect the micromorphology of carriers, which was the important influential factor for loading or releasing drugs. To our delight, complex VIII-3 (LC = 0.32, total releasing amount/time = 99.8%/168 h) showed a macroporous framework with the drug evenly distributed across the opening network and staged drug-releasing performance that deserved further study as a nanopesticide.