192575-90-9

Basic information

• Product Name: (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one
• Synonyms: 2H-1,3-diazepin-2-one, hexahydro-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-4,7-bis(phenylmethyl)-, (4R,5S,6S,7R)-
• CAS NO: 192575-90-9
• Molecular Formula: C₂₅H₃₄N₂O₅
• Molecular Weight: 442.5479
• Mol File: 192575-90-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 674.1°C at 760 mmHg
• Flash Point: 361.5°C
• Density: 1.241g/cm³
• Vapor Pressure: 4.32E-19mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one(192575-90-9)
• EPA Substance Registry System: (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one(192575-90-9)

Safety Data

• Hazardous Substances Data: 192575-90-9(Hazardous Substances Data)

Usage

Description

(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one is a complex organic compound characterized by its multiple functional groups, including two benzyl groups, two hydroxyl groups, and two hydroxypropyl groups attached to a diazepan-2-one ring. (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one is likely to exhibit both hydrophilic and hydrophobic properties due to its hydroxyl and benzyl groups, respectively. The presence of the diazepan-2-one ring and the compound's chirality, as indicated by the (4R,5S,6S,7R) configuration, suggest potential biological activity and interactions with other molecules, which may have pharmacological implications.

Uses

Used in Pharmaceutical Industry:
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one is used as a potential pharmaceutical candidate for various applications due to its complex structure and chirality. (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one's hydrophilic and hydrophobic properties, along with its potential biological activity, make it a promising candidate for drug development and therapeutic interventions.
Used in Drug Delivery Systems:
In the field of drug delivery, (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one can be utilized as a carrier or component in the design of novel drug delivery systems. Its dual hydrophilic and hydrophobic nature may facilitate the encapsulation and controlled release of therapeutic agents, improving their bioavailability and targeting efficiency.
Used in Chemical Research:
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-hydroxypropyl)-1,3-diazepan-2-one is also used in chemical research as a model compound to study the effects of chirality and functional group interactions on compound properties and reactivity. This can contribute to the development of new synthetic methods and the understanding of structure-activity relationships in various chemical and biological contexts.

Upstream product

• 153223-14-4 (4R,5S,6S,7R)-1,3-Diallyl-4,7-dibenzyl-5,6-dihydroxy-[1,3]diazepan-2-one 

Relevant articles and documents

Functionalized aliphatic P2/P2' analogs of HIV-1 protease inhibitor DMP323

A series of analogs of HIV protease inhibitor DMP323 containing functionalized aliphatic P2/P2' groups was prepared and evaluated for HIV protease inhibition and antiviral activity in a cell-based assay. Asymmetric compounds with a 5-hydroxypentyl substituent at P2 and a benzylic substituent at P2' showed increased potency over the corresponding symmetrically substituted analogs.