192642-85-6

Basic information

• Product Name: 2-(5-bromopyridin-2-yl)acetic acid
• Synonyms: 5-Bromopyridine-2-acetic acid;5-BroMopyridin-2-acetic acid;5-BroMo-2-pyridineacetic acid, 98%;(5-broMopyridin-2-yl)acetic acid;5-BroMo-2-pyridylacetic acid;2-(5-Bromopyridin-2-yl)ethanoic acid, 5-Bromo-2-(carboxymethyl)pyridine;2-(5-bromopyridin-2-yl)acetic acid
• CAS NO: 192642-85-6
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.04
• Mol File: 192642-85-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 120-123℃
• Boiling Point: 326.2ºC at 760 mmHg
• Flash Point: 151.1ºC
• Appearance: /
• Density: 1.71g/cm3
• Vapor Pressure: 8.89E-05mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.81±0.10(Predicted)
• CAS DataBase Reference: 2-(5-bromopyridin-2-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-bromopyridin-2-yl)acetic acid(192642-85-6)
• EPA Substance Registry System: 2-(5-bromopyridin-2-yl)acetic acid(192642-85-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 192642-85-6(Hazardous Substances Data)

Usage

General Description

2-(5-bromopyridin-2-yl)acetic acid is a chemical compound with the molecular formula C8H7BrNO2. It is a derivative of pyridine, containing a bromine atom and an acetic acid group attached to the pyridine ring. 2-(5-bromopyridin-2-yl)acetic acid is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block for the synthesis of other chemical compounds. It may also have applications in the development of new drugs or as a reagent in chemical reactions. Additionally, its structural properties and reactivity make it a valuable tool in the study and manipulation of biological systems.

InChI:InChI=1/C7H6BrNO2/c8-5-1-2-6(9-4-5)3-7(10)11/h1-2,4H,3H2,(H,10,11)

Upstream product

• 223463-13-6 2-iodo-5-bromopyridine 
• 626-55-1 3-Bromopyridine 
• 1215098-80-8 diethyl 2-(5-bromopyridin-2-yl)malonate 
• 2402-97-3 3-bromopyridine N-oxide 
• 192642-83-4 5-(5-bromo-1H-2-pyridinylidene)-2,2-dimethyl-[1,3]dioxane-4',6-dione 

Downstream Products

• 917023-06-4 methyl 2-(5-bromopyridin-2-yl)acetate 

Relevant articles and documents

TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS

A compound of formula I wherein: n is 1 or 2: p is 0 or 1; R1 is optionally one or more halo or methyl groups; R2a and R2b are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R2c and R2d are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R3a and R3b are independently selected from H and Me; R4 is either H or Me; R5 is either H or Me; R6a and R6b are independently selected from H and Me; A is either (i) optionally substituted phenyl; (ii) optionally substituted naphthyl; or (iii) optionally substituted C5-12 heteroaryl.

C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

Triazolopyridines. 18.1 nucleophilic substitution reactions on triazolopyridines; a new route to 2,2'-Bipyridines

The synthesis of some 5-, 6-, and 7-halogenotriazolopyridines is described and their reactions with nucleophiles. The formation or 7,7'-bitriazolopyridines provides a new synthesis of 2,2'-bipyridines.