192711-05-0

Basic information

• Product Name: (Z)-3'-hydroxy-3,4,4',5-tetramethoxy-2'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)stilbene
• CAS NO: 192711-05-0
• Molecular Weight: 662.645
• Mol File: 192711-05-0.mol

Chemical Properties

• CAS DataBase Reference: (Z)-3'-hydroxy-3,4,4',5-tetramethoxy-2'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)stilbene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3'-hydroxy-3,4,4',5-tetramethoxy-2'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)stilbene(192711-05-0)
• EPA Substance Registry System: (Z)-3'-hydroxy-3,4,4',5-tetramethoxy-2'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)stilbene(192711-05-0)

Safety Data

• Hazardous Substances Data: 192711-05-0(Hazardous Substances Data)

Upstream product

• 109971-63-3 (Z)-3-methoxy-6-(3,4,5-trimethoxystyryl)benzene-1,2-diol 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 108683-61-0 triphenyl(3,4,5-trimethoxybenzyl)phosphonium chloride 
• 109971-68-8 (Z)-1-[3',4',5'-trimethoxyphenyl]-2-[(2'',3''-di[(tert-butyldimethylsilyl)oxy]-4''-methoxy)phenyl]ethene 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 

Relevant articles and documents

Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series)

(E)-3-(β-D-Glucopyranosyloxy)-4',5-dihydroxystilbene (resveratrol 3-β-D-glucoside, piceid), (Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene (combretastatin A-1), (Z)-3'-hydroxy-3,4,4', 5-tetramethoxystilbene (combretastatin A-4), (Z)-2'-hydroxy-3,4,4',5-tetramethoxystilbene (combretastatin iso-A-4), α,β-dihydro-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene (combretastatin B-1), the corresponding glucosides, and related compounds have been synthesized via Wittig reactions followed by,glucosylation under phase-transfer catalysis. Most of the compounds synthesized have been tested with respect to biological activity (cytostatic, cytotoxic, antimitotic, neurotoxic, antiplatelet aggregation activity).