19275-29-7Relevant articles and documents
An efficient method for the production of terminal alkynes from 1,1-dibromo-1-alkenes and its application in the total synthesis of natural product dihydroxerulin
Liu, Shihui,Chen, Xiaobei,Hu, Yanwei,Yuan, Laiqi,Chen, Shaohua,Wu, Ping,Wang, Wei,Zhang, Shilei,Zhang, Wei
, p. 553 - 560 (2015/03/05)
An efficient method of preparing various terminal alkynes from 1,1-dibromo-1-alkenes by using TBAF (tetra-n-butylammonium fluoride) as a base and triphenylphosphane as a reductant was developed. This method is strong base and low/high temperatures free, and can tolerate a broad range of substrates. These advantages were well demonstrated by the application of this method to the total synthesis of polyene natural product dihydroxerulin.
5-Nitro-2-furylvinylation of Secondary and Tertiary Amines
Vegh, Daniel,Kovac, Jaroslav,Dandarova, Miloslava,Ivanco, Lubor
, p. 155 - 162 (2007/10/02)
Reaction of 12 secondary amines and trimethylamine with (Z) and (E)-5-nitro-2-furylvinylbromide (I) was studied.Whereas the enamine II, obtained from secondary amines, have the E configuration, the quaternisation of trimethyamine affords stereospecifically the corresponding (Z) or (E) vinylammonium salts III.