19275-29-7

Basic information

• Product Name: 2-ETHYNYL-5-NITRO-FURAN
• Synonyms: 2-ETHYNYL-5-NITRO-FURAN
• CAS NO: 19275-29-7
• Molecular Formula: C6H3NO3
• Molecular Weight: 137.09292
• Mol File: 19275-29-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-ETHYNYL-5-NITRO-FURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYNYL-5-NITRO-FURAN(19275-29-7)
• EPA Substance Registry System: 2-ETHYNYL-5-NITRO-FURAN(19275-29-7)

Safety Data

• Hazardous Substances Data: 19275-29-7(Hazardous Substances Data)

Upstream product

• 63708-87-2 2-(β,β-dibromovinyl)-5-nitrofuran 
• 59563-50-7 (Z)-2-bromo-1-(5-nitro-2-furyl)ethylene 
• 71258-92-9 1,2-dibromo-1-(5-nitro-2-furyl)ethane 
• 67363-72-8 2-bromo-1-(5-nitro-2-furyl)ethylene 

Relevant articles and documents

An efficient method for the production of terminal alkynes from 1,1-dibromo-1-alkenes and its application in the total synthesis of natural product dihydroxerulin

An efficient method of preparing various terminal alkynes from 1,1-dibromo-1-alkenes by using TBAF (tetra-n-butylammonium fluoride) as a base and triphenylphosphane as a reductant was developed. This method is strong base and low/high temperatures free, and can tolerate a broad range of substrates. These advantages were well demonstrated by the application of this method to the total synthesis of polyene natural product dihydroxerulin.

5-Nitro-2-furylvinylation of Secondary and Tertiary Amines

Reaction of 12 secondary amines and trimethylamine with (Z) and (E)-5-nitro-2-furylvinylbromide (I) was studied.Whereas the enamine II, obtained from secondary amines, have the E configuration, the quaternisation of trimethyamine affords stereospecifically the corresponding (Z) or (E) vinylammonium salts III.