192755-59-2

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 192754-25-9 (3S)-2-oxo-3-(benzoylamino)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-acetic acid methyl ester 
• 175211-40-2 (S)-(3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine)-1-acetic acid methyl ester 
• 175211-39-9 ((S)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-carbamic acid tertbutyl ester 
• 741231-30-1 (3-amino-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-yl)-acetic acid methyl ester 
• 192754-23-7 (3S)-2-Oxo-3-benzoylamino-5-(3-phenylpropionyl)-2,3,4,5-tetrahydro-1H-1,5-benzo diazepine-1-acetic acid methyl ester 
• 175211-37-7 (S)-2-((tert-butoxycarbonyl)amino)-3-((2-nitrophenyl)amino)-propanoic acid 
• 175211-38-8 (S)-3-((2-aminophenyl)amino)-2-((tert-butoxycarbonyl)amino)-propanoic acid 

Relevant academic research and scientific papers

A practical synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1,5-benzodiazepine-1- acetic acid methyl ester as a conformationally restricted dipeptido-mimetic for caspase-1 (ICE) inhibitors

A simple and versatile method for the synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1,5-benzodiazepine-1- acetic acid methyl ester (4), a dipeptide mimetic, has been developed. The regioselective functionalization of the N1 and N5 r