192764-19-5

Upstream product

• 91190-38-4 N-benzyl-2,3-O-isopropylidene-D-glyceraldehyde nitrone 
• 192764-11-7 N-Benzyl-N-[(S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propyl]-hydroxylamine 

Downstream Products

• 192764-24-2 (2S,3S)-3-Benzylamino-pentane-1,2-diol 
• 192764-30-0 (2S,3S)-3-Benzylamino-1-(tert-butyl-dimethyl-silanyloxy)-pentan-2-ol 

Relevant academic research and scientific papers

Stereocontrolled addition of Grignard reagents to α-alkoxy nitrones. Synthesis of syn and anti 3-amino-1,2-diols

The stereoselective addition of Grignard reagents to α-alkoxy nitrones has been achieved with excellent stereocontrol using ZnBr2 and Et2AlCl as precomplexing agents to obtain the corresponding syn- and anti- adducts, respectively. The obtained hydroxylamines have been transformed into valuable 3-amino-1,2-diols.