192817-90-6

Basic information

• Product Name: Phosphonic acid, [2-[2-(4-morpholinyl)phenyl]-2-oxoethyl]-, dimethyl ester
• CAS NO: 192817-90-6
• Molecular Formula: C14H20NO5P
• Molecular Weight: 313.29
• Mol File: 192817-90-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-[2-(4-morpholinyl)phenyl]-2-oxoethyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-[2-(4-morpholinyl)phenyl]-2-oxoethyl]-, dimethyl ester(192817-90-6)
• EPA Substance Registry System: Phosphonic acid, [2-[2-(4-morpholinyl)phenyl]-2-oxoethyl]-, dimethyl ester(192817-90-6)

Safety Data

• Hazardous Substances Data: 192817-90-6(Hazardous Substances Data)

Upstream product

• 393-52-2 2-Fluorobenzoyl chloride 
• 443-26-5 2-fluoro-benzoic acid ethyl ester 
• 192817-79-1 ethyl 2-(morpholin-4-yl)-benzoate 
• 756-79-6 dimethyl methane phosphonate 

Downstream Products

• 192818-05-6 dimethyl 1-diazo-2-oxo-2-(2-morpholinophenyl)ethylphosphonate 

Relevant articles and documents

Tandem Wolff rearrangement-'tert-amino effect' sequence: Synthesis of 2-oxoindolinium enolate derivatives

The thermolysis of 1-diazo-2-oxo-(2-N,N-disubstituted aminophenyl)ethylphosphonates 1 gave rise to 2-oxoindolinium enolate derivatives 4 through Wolff rearrangement and interaction of the tert-amino moiety with the ketene functionality. Variable amounts of either ammonium ylides 5 or of products resulting from their transformations were also formed during the course of the reaction. If the amino moiety was substituted by a benzyl or an allyl group, indolinones, resulting from [1,3] or [1,2] benzylic or allylic shifts, were isolated in place of compounds 4 and 5.