192861-86-2

Upstream product

• 288-88-0 1,2,4-Triazole 
• 192862-17-2 2-[difluoro(methylthio)methyl]-2-(2,4-difluorophenyl)oxirane 
• 60-29-7 diethyl ether 
• 192862-11-6 1-(2,4-difluorophenyl)-2,2-difluoro-2-(methylthio)-1-ethanone 
• 192862-10-5 2',4'-difluoro-α-(methylthio)acetophenone 
• 102429-07-2 2-bromo-2',4'-difluoroacetophenone 

Downstream Products

• 192861-91-9 3,3-difluoro-2-(2',4'-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)propan-2-ol 

Relevant academic research and scientific papers

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety

New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus

Triazole derivative and pharmaceutical comprising the same as an effective ingredient

Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1)