192927-28-9Relevant articles and documents
Sequential decarboxylative azide-alkyne cycloaddition and dehydrogenative coupling reactions: One-pot synthesis of polycyclic fused triazoles
Bharathimohan, Kuppusamy,Ponpandian, Thanasekaran,Ahamed, A. Jafar,Bhuvanesh, Nattamai
, p. 3031 - 3037 (2014)
Herein, we describe a one-pot protocol for the synthesis of a novel series of polycyclic triazole derivatives. Transition metalcatalyzed decarboxylative CuAAC and dehydrogenative cross coupling reactions are combined in a single flask and achieved good yi
Gas-phase pyrolysis of 1-(2-azidophenyl)imidazole
Blake, Alexander J.,Clark, Bernard A. J.,McNab, Hamish,Sommerville, Craig C.
, p. 1605 - 1608 (1997)
Flash vacuum pyrolysis (FVP) of the azide 4 leads to imidazo[1,2-a]benzimidazole 8 exclusively, via highly regioselective insertion of the triplet nitrene intermediate 5 into the 2-CH bond of the imidazole ring. The X-ray crystal structure and NMR spectro
A catalytic intramolecular nitrene insertion into a copper(i)-N-heterocyclic carbene bond yielding fused nitrogen heterocycles
Fauché, Kévin,Nauton, Lionel,Jouffret, Laurent,Cisnetti, Federico,Gautier, Arnaud
, p. 2402 - 2405 (2017/02/23)
N-(2-Azidophenyl)azolium salts were easily prepared and reacted with copper(i) under conditions allowing the formation of NHC complexes. Under these conditions, the formation of benzimidazo-fused heterocycles occurred under catalytic, efficient and very mild conditions. This reaction is proposed to proceed via dinitrogen elimination and imido/nitrene-NHC cyclization.
