192989-91-6

Basic information

• Product Name: 1H-Indole-2,3-dione, 5-[4-[4-(phenylmethyl)-1-piperidinyl]-1-butynyl]-
• CAS NO: 192989-91-6
• Molecular Formula: C24H24N2O2
• Molecular Weight: 372.467
• Mol File: 192989-91-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2,3-dione, 5-[4-[4-(phenylmethyl)-1-piperidinyl]-1-butynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2,3-dione, 5-[4-[4-(phenylmethyl)-1-piperidinyl]-1-butynyl]-(192989-91-6)
• EPA Substance Registry System: 1H-Indole-2,3-dione, 5-[4-[4-(phenylmethyl)-1-piperidinyl]-1-butynyl]-(192989-91-6)

Safety Data

• Hazardous Substances Data: 192989-91-6(Hazardous Substances Data)

Upstream product

• 20780-76-1 5-iodoisatin 
• 192989-99-4 4-benzyl-1-(3-Butynyl)piperidine 
• 121-44-8 triethylamine 

Relevant articles and documents

4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists

Novel 4-substituted piperidine analogs, pharmaceutical compositions containing the same and the method of using 4-substituted piperidine analogs as selectively active antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes for treating conditions such as stroke, cerebral ischemia, central nervous system trauma, hypoglycemia, anxiety, convulsions, aminoglycoside antibiotics-induced hearing loss, migraine headaches, glaucoma, CMV retinitis, chronic pain, opioid tolerance or withdrawals, or neurodegenerative disorders, such as lathyrism, Alzheimer's Disease, Parkinsonism and Huntington's Disease are described. Also described are novel methods for preparing 4-substituted piperidine analogs and novel intermediates of the 4-substituted piperidine analogs.