19302-30-8Relevant academic research and scientific papers
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
Salomó, Ernest,Gallen, Albert,Sciortino, Giuseppe,Ujaque, Gregori,Grabulosa, Arnald,Lledós, Agustí,Riera, Antoni,Verdaguer, Xavier
supporting information, p. 16967 - 16970 (2018/12/14)
A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst containing a P-stereogenic MaxPHOX ligand is described for the direct asymmetric hydrogenation of N-methyl and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile tetrahydrofuran ligand allows for effective activation and reactivity, even at low temperatures. Density functional theory calculations allowed the rationalization of the stereochemical course of the reaction.
Chirality transcription and amplification by [2]pseudorotaxanes
Kuwahara, Shunsuke,Chamura, Rie,Tsuchiya, Sho,Ikeda, Mari,Habata, Yoichi
supporting information, p. 2186 - 2188 (2013/04/10)
Chirality transcription and amplification by the formation of chiral [2]pseudorotaxanes by an achiral crown ether having the 2′, 2′′-quaterphenyl group and chiral sec-ammonium ions are reported. It was revealed that the absolute configurations of the chiral sec-ammonium ions can be detected directly from the CD spectra of the chiral [2]pseudorotaxanes.
The amide bond rotation controlled by an unusual C- H···O hydrogen bonding that favors the 1,4-phenyl radical migration
Fuentes, Lilia,Quintero, Leticia,Cordero-Vargas, Alejandro,Eustaquio, Cesar,Terán, Joel L.,Sartillo-Piscil, Fernando
supporting information; experimental part, p. 3630 - 3632 (2011/07/31)
Experimental evidence in support of the presence of a weak C-H···O hydrogen bonding that favors 1,4-phenyl radical migration in a chiral amide is provided.
