19313-85-0

Basic information

• Product Name: 4-(propionylamino)benzoic acid
• Synonyms: 4-(propionylamino)benzoic acid;benzoic acid, 4-[(1-oxopropyl)amino]-;Albb-010045;4-(propionylamino)benzoic acid(SALTDATA: FREE);4-(1-oxopropylamino)benzoic acid;4-(propanoylamino)benzoic acid;4-propionamidobenzoic acid
• CAS NO: 19313-85-0
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.2
• Mol File: 19313-85-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 440.3°C at 760 mmHg
• Flash Point: 220.1°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 1.58E-08mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 4-(propionylamino)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(propionylamino)benzoic acid(19313-85-0)
• EPA Substance Registry System: 4-(propionylamino)benzoic acid(19313-85-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 19313-85-0(Hazardous Substances Data)

Usage

General Description

4-(propionylamino)benzoic acid is a chemical compound with the molecular formula C11H11NO3. It is a derivative of benzoic acid with a propionylamino group attached to the fourth carbon of the benzene ring. 4-(propionylamino)benzoic acid is commonly used in pharmaceutical and medical research as a building block in the synthesis of various drugs and compounds. It has also been studied for its potential therapeutic applications in the treatment of inflammatory conditions and cancer. The chemical properties and biological activities of 4-(propionylamino)benzoic acid make it a valuable compound for further research and development in the field of medicine and pharmaceuticals.

InChI:InChI=1/C10H11NO3/c1-2-9(12)11-8-5-3-7(4-6-8)10(13)14/h3-6H,2H2,1H3,(H,11,12)(H,13,14)

Upstream product

• 150-13-0 4-amino-benzoic acid 
• 123-62-6 propionic acid anhydride 
• 79-03-8 propionyl chloride 

Downstream Products

• 934221-25-7 N-(N-4-propionamidobenzoyl-L-phenylalanyl)-L-phenylalanine methyl ester 
• 934221-26-8 N-(N-4-propionamidobenzoyl-L-phenylalanyl)-4-nitro-L-phenylalanine methyl ester 
• 142962-36-5 1-[4-(N-propionylamino)-benzoyl]-4-[2-(4-chlorophenyl)ethyl]-piperazine 
• 1026348-44-6 3-Nitro-4-propionylamino-benzoyl chloride 
• 170804-52-1 3-Nitro-4-propionylamino-benzoic acid 

Relevant articles and documents

INHIBITORS OF CYCLIN-DEPENDENT KINASES

Provided herein are inhibitors of cyclin-dependent kinases (CDKs), pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

Synthesis and biological evaluation of Matijing-Su derivatives as potent anti-HBV agents

A series of Matijing-Su (MTS, N-(N-benzoyl-l-phenylalanyl)-O-acetyl-l- phenylalanol) derivatives were synthesized and evaluated for their anti-hepatitis B virus (HBV) activity in 2.2.15 cells. The IC50 of compounds 14a (0.71 μM), 13c (2.85 μM), 13b (4.37 μM), etc. and the selective index of 13g (161.01), 13c (90.45), 13a (85.09) etc. of the inhibition on the replication of HBV DNA were better than those of the positive control lamivudine (IC50: 82.42 μM, SI: 41.59). Compounds 13o, 13p, and 16a also exhibited significant anti-HBV activity.