19315-36-7Relevant academic research and scientific papers
The application of (Z)-3-aryl-3-haloenoic acids to the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2(5H)-ones
Gupton, John T.,Telang, Nakul,Banner, Edith J.,Kluball, Emily J.,Hall, Kayleigh E.,Finzel, Kara L.,Jia, Xin,Bates, Spencer R.,Welden, R. Scott,Giglio, Benjamin C.,Eaton, James E.,Barelli, Peter J.,Firich, Lauren T.,Stafford, John A.,Coppock, Matthew B.,Worrall, Eric F.,Kanters, Rene P.F.,Keertikar, Kerry,Osterman, Rebecca
experimental part, p. 9113 - 9122 (2011/01/12)
Studies directed at the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2(5H)- ones from (Z)-3-aryl-3-haloenoic acids are described. The successful strategy relies on the preparation of (Z)-3-aryl-3-haloenoic acids from acetophenones through the corresponding
Synthesis and stereochemistry of β-aryl-β-haloacroleins: Useful intermediates for the preparation of (Z) and (E)-2-en-4-ynecarbaldehydes and for the synthesis of rubrolides
Prim, Damien,Fuss, Alexia,Kirsch, Gilbert,Silva, Artur M. S.
, p. 1175 - 1180 (2007/10/03)
The synthesis of α-substituted β-aryl-β-haloacroleins by two different pathways is presented. The determination of their stereochemistry by NOE experiments is reported for the first time. Furthermore, we describe the preparation of 2-en-4-ynecarbaldehydes
