193156-92-2Relevant academic research and scientific papers
α-Galactose based neoglycopeptides. Inhibition of verotoxin binding to globotriosylceramide
Arya, Prabhat,Kutterer, Kristina M.K.,Qin, Huiping,Roby, Johanne,Barnes, Michael L.,Lin, Shuqiong,Lingwood, Clifford A.,Peter, Markus G.
, p. 2823 - 2833 (2007/10/03)
Solution and solid phase strategies for the synthesis of α-galactose based neoglycopeptide derivatives 2-13 were developed. Neoglycopeptides generated were tested for the inhibition of verotoxin binding to globotriosylceramide (Gb3) using ELISA. Among all
Stereoselective synthesis of neo-C-glycopeptide building blocks: Towards a flexible and control-oriented design as probes for carbohydrate-protein interactions
Arya, Prabhat,Dion, Sylvain,Shimizu, George K. H.
, p. 1537 - 1542 (2007/10/03)
Neo-C-glycopeptides (1-4) have been synthesized as building blocks to obtain higher neo-C-glycopeptides as probes for studying carbohydrate-protein interactions. A convergent approach for the synthesis of 4 has been developed, in which two galactose units are attached to a glycine derivative in a stepwise procedure (reductive amination followed by amide coupling) and finally coupling to the protected dipeptide having a free amino group on the side chain.
