19316-86-0Relevant academic research and scientific papers
Novel chalcogenides of thymidine and uridine: synthesis, properties and applications
Sivapriya, Kirubakaran,Suguna, Perumal,Shubashree,Sridhar, Perali Ramu,Chandrasekaran, Srinivasan
, p. 1151 - 1158 (2007)
A facile and efficient methodology has been developed for the synthesis of dithymidine and di-uridine derived disulfides using benzyltriethylammonium tetrathiomolybdate as a sulfur transfer reagent. However, a similar reaction of thymidine derivative with tetraethylammonium tetraselenotungstate as a selenium transfer reagent resulted in the formation of an unexpected cyclic diselenide. The disulfide derivatives of nucleosides have been used as precursors in a tandem disulfide cleavage-Michael addition/ring opening reactions to construct aminoacid and carbocyclic derivatives of nucleosides.
