1932015-48-9Relevant articles and documents
An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis
Goss, Rebecca J. M.,Lanceron, Simon,Roy, Abhijeet Deb,Sprague, Simon,Nur-e-Alam, Mohammed,Hughes, David L.,Wilkinson, Barrie,Moss, Steven J.
, p. 698 - 702 (2010)
Rapamycin is a drug with several important clinical uses. Its complex structure means that total synthesis of this natural product and its analogues is demanding and lengthy. A more expeditious approach is to utilise biosynthesis to enable the generation