1932285-09-0

Basic information

• Product Name: TERT-BUTYL 6-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE
• Synonyms: TERT-BUTYL 6-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE
• CAS NO: 1932285-09-0
• Molecular Formula: C11H17NO3
• Molecular Weight: 211.25758
• Mol File: 1932285-09-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 308.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.173±0.06 g/cm3(Predicted)
• PKA: -1.10±0.20(Predicted)
• CAS DataBase Reference: TERT-BUTYL 6-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 6-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE(1932285-09-0)
• EPA Substance Registry System: TERT-BUTYL 6-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE(1932285-09-0)

Safety Data

• Hazardous Substances Data: 1932285-09-0(Hazardous Substances Data)

Upstream product

• 149494-50-8 (-)-(1S,1'R)-2-(1'-Phenylethyl)-2-azabicyclo<2.2.1>hept-5-ene 
• 702666-72-6 tert-butyl (1S,4R)-2-azabicyclo[2.2.1]heptan-5-en-2-carboxylate 
• 130931-83-8 (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one 
• 198835-01-7 (1S,4R,6S)-tert-butyl 6-hydroxy-2-azabicyclo[2,2,1]heptane-2-carboxylate 
• 1099570-25-8 tert-butyl (1RS,4SR,6RS)-6-hydroxy-2-azabicyclo[2.2.1] heptane-2-carboxylate 
• 542-92-7 cyclopenta-1,3-diene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1099570-25-8 6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 198835-02-8 C₁₁H₁₉NO₃ 
• 1099570-25-8 tert-butyl 6-hydroxy-2-azabicyclo[2,2,1]heptane-2-carboxylate 
• 188345-71-3 2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]hept-5-ene 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 1005077-74-6 (1S,4S,6R)-tert-butyl 6-amino-2-azabicyclo[2,2,1]heptane-2-carboxylate 
• 1005077-74-6 exo-6-amino-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 1005077-74-6 endo-6-amino-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS

Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein HET, R1, R2, R3, R4, R5, L, L1, X1, X2, X3 and q are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.

Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist

A class of novel pyrimidine derivatives bearing diverse conformationally restricted azabicyclic ether/amine were designed, synthesized and evaluated for their GPR119 agonist activities against type 2 diabetes. Most compounds exhibited superior hEC50

Synthesis of novel azanorbornylpurine derivatives

Azanorbornylpurine derivatives were prepared by Mitsunobu reaction of appropriate hydroxyazanorbornane derivative with 6-chloropurine or construction of purine base at azanorbornylamines. The prepared target compounds were evaluated for antiviral activity and effect on neuronal and muscle nicotinic acetylcholine receptors.