193292-60-3Relevant academic research and scientific papers
Studies on the synthesis of the quartromicins: Partial stereochemical assignment of quartromicins A3 and D3 and diastereoselective synthesis of the endo- and exo-spirotetronate subunits
Roush, William R,Barda, David A,Limberakis, Chris,Kunz, Roxanne K
, p. 6433 - 6454 (2007/10/03)
A partial stereochemical assignment of quartromicins A3 and D3 is presented, along with diastereoselective syntheses of the endo- and exo-spirotetronates 1 and 2, corresponding to the galacto and agalacto fragments of the proposed quartromicin stereostructure. The key steps of these syntheses are highly enantio- and diastereoselective Lewis acid catalyzed Diels-Alder reactions of 1,1,3,4-tetrasubstituted diene 24.
