193342-98-2Relevant academic research and scientific papers
Acyloxybenzyl and Alkoxyalkyl Prodrugs of a Fosmidomycin Surrogate as Antimalarial and Antitubercular Agents
Courtens, Charlotte,Risseeuw, Martijn,Caljon, Guy,Cos, Paul,Van Calenbergh, Serge
, p. 986 - 989 (2018)
Two classes of prodrugs of a fosmidomycin surrogate were synthesized and investigated for their ability to inhibit in vitro growth of P. falciparum and M. tuberculosis. To this end, a novel efficient synthesis route was developed involving a cross metathe
Convenient Method for the Preparation of Some Polyhydroxamic Acids: Michael Addition of Amines to Acrylohydroxamic Acid Derivatives
Koshti, Nirmal M.,Jacobs, Hollie K.,Martin, Patrick A.,Smith, Paul H.,Gopalan, Aravamudan S.
, p. 5157 - 5160 (2007/10/02)
Reagents 1, 2, and 3 are readily prepared by the reaction of the appropriate hydroxylamine derivatives with acryloyl chloride.They undergo Michael addition with a variety of amines to give the corresponding O-protected hydroxamate derivatives in moderate
