193469-37-3

Upstream product

• 49823-14-5 1-(2-phenylethyl)-1H-imidazole 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 193469-35-1 4-[1-(2-phenylethyl)-1H-imidazol-2-yl]-1-benzyl-4-piperidinol 

Downstream Products

• 279253-88-2 3-bromo-5,6-dihydro-1'-benzylspiro[11H-imidazo[2,1-b][3]benzazepine-11,4'-piperidine] 

Relevant academic research and scientific papers

Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines

Clinical doses of available H1 antihistamines are limited mainly by sedative side effects. However, higher doses are often required to obtain optimal therapeutic activity, especially in dermatology. We report the synthesis of three norpiperidin

Antihistaminic spiro compounds

This invention concerns the compounds of formula 1 or a prodrug, a N-oxide, an addition salt, a quaternary amine or a stereochemically isomeric form thereof wherein R1, R2, —A—B—, L, and n have the meaning given in the description. The invention relates to preparations and compositions of the present compounds and their use as medicines.