193532-21-7Relevant articles and documents
Aberrant buildup of all-Trans-retinal dimer, a nonpyridinium bisretinoid lipofuscin fluorophore, contributes to the degeneration of the retinal pigment epithelium
Zhao, Junli,Liao, Yi,Chen, Jingmeng,Dong, Xinran,Gao, Zhan,Zhang, Houjian,Wu, Xiaodan,Liu, Zuguo,Wu, Yalin
, p. 1063 - 1075 (2017)
PURPOSE. Nondegradable fluorophores that accumulate as deleterious lipofuscin of RPE are involved in pathological mechanisms leading to the degeneration of RPE in AMD. A2E, a major component of RPE lipofuscin, could cause damage to RPE cells. Nevertheless
Substituted Cyclohexadienals - Syntheses and Applications
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Page/Page column 18-19, (2010/11/28)
The present invention is generally directed to the use of L-proline and certain derivatives thereof to catalyze the asymmetric self-condensation of α,β-unsaturated aldehydes to form homodimer and heterodimer cyclohexadienals. Reaction conditions are mild