193538-22-6 Usage
Description
1-(4-METHOXY-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE is a chemical compound with the formula C15H21NO3·HCl. It is a piperidine derivative known for its potential applications in the development of new drugs and research in molecular biology. 1-(4-METHOXY-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE is soluble in water, ethanol, and chloroform, and its hydrochloride salt form provides enhanced stability and solubility in aqueous solutions, making it a versatile compound for various laboratory and industrial applications.
Uses
Used in Pharmaceutical Industry:
1-(4-METHOXY-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE is used as a precursor in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs. Its structural properties allow for the creation of a wide range of medicinal compounds.
Used in Organic Chemistry Research:
In the field of organic chemistry, 1-(4-METHOXY-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE is used as a key compound in the synthesis of complex organic molecules. Its versatility in solubility and stability makes it an ideal candidate for research and development in molecular biology.
Used in Laboratory Applications:
Due to its enhanced stability and solubility, 1-(4-METHOXY-BENZYL)-PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE is used in laboratory settings for various experiments and analyses. Its properties make it suitable for a range of chemical reactions and tests, contributing to the advancement of scientific knowledge in related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 193538-22-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,5,3 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 193538-22:
(8*1)+(7*9)+(6*3)+(5*5)+(4*3)+(3*8)+(2*2)+(1*2)=156
156 % 10 = 6
So 193538-22-6 is a valid CAS Registry Number.
193538-22-6Relevant articles and documents
Novel indirect AMP-activated protein kinase activators: Identification of a second-generation clinical candidate with improved physicochemical properties and reduced hERG inhibitory activity
Kuramoto, Kazuyuki,Sawada, Yuki,Yamada, Tomohiro,Nagashima, Takeyuki,Ohnuki, Kei,Shin, Takashi
, p. 452 - 465 (2020)
This study reports the synthesis and evaluation of novel indirect AMP-activated protein kinase (AMPK) activators. The series of compounds selectively inhibited cell growth in several human breast cancer cell lines by activating AMPK. We performed back-up medicinal chemistry synthetic research on ASP4132, a previously reported as a compound for clinical development that acts as an indirect AMPK activator. This led to the successful identification of 4-({4-[5-({1-[(5-ethoxypyrazin-2-yl)methyl]-4-fluoropiperidin-4-yl}methoxy)-3-methylpyridine-2-carbonyl]piperazin-1-yl}methyl)benzonitrile succinate (27b), a potent, highly aqueous soluble and metabolically stable compound in human hepatocytes. Compound 27b also showed weaker human Ether-a-go-go Related Gene (hERG) inhibitory activity than that of compound 13 and ASP4132. Therefore, 27b was a promising AMPK activator and a second-generation clinical candidate for treatment for human cancer.
