193539-69-4Relevant academic research and scientific papers
Synthesis and spectral properties of 2,3-dihydro-4-(paramethylphenyl)- 7-[(o-, m-, and p-substituted)phenoxy]-1H-1,5-benzodiazepine-2-thiones
Cortes,Torres
, p. 953 - 956 (1997)
A series of twelve new 2,3-dihydro-4-(para-methylphenyl)-7-[(o-, m-, and p-substituted)phenoxy]-1H-1,5-benzodiazepine-2-thiones, which have potentially useful pharmacological properties, has been synthesized by condensing the 3,3-dimercapto-1-(p-methylphenyl)-2-propen-1-one with 3,4- diaminophenyl-R-phenyl ethers. The structure of all products was corroborated by ir; 1H-nmr; 13C-nmr and ms.
Synthesis and spectral properties of 2-methylthio-3H-7-[(o-; m- and p-substituted)phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines
Cortes, Eduardo Cortes,Romero, Cristina A. Cortes,Mellado, Olivia Garcia
, p. 1321 - 1324 (2007/10/03)
A series of eleven new 2-methylthio-3H-7-[(o-; m- and p-substituted) phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines, which have potentially useful pharmacological activities, has been synthesized by condensing the 4-[(o-; m- and p-R1)phenoxy]-1,2-phenylendiamines with 3,3-dimercapto-l-(p-R2-phenyl)-2-propen-1-one. Afterward the 1H-[1,5]benzodiazepine-2-thiones obtained were treated with sodium hydride and methyl iodide. The structure of all products was corroborated by ir, 1H nmr, 13C nmr and ms.
Synthesis and spectral properties of 5-methylthio-4H-1-(p-substituted- phenyl)-3a-(p-substituted-phenyl)-9-([(m-; and p-substituted)-phenoxyl-3a,4- dihydro[1,2,4]oxadiazolo[4,5-a][1,5]benzodiazepines
Cortes, Eduardo Cortes,Mellado, Olivia Garcia,Cruz, Elide Hernandez
, p. 477 - 480 (2007/10/03)
The preparation of eight novel substituted [1,2,4]oxadiazolo[4,5- a][1,5]benzodiazepines which have potentially useful pharmacological properties; by 1,3-cycloaddition of benzonitrile oxides, generated in situ from benzohydroxamoyl chloride and triethylamine, to 1,5-benzodiazepine derivatives is described. The structure of all products was corroborated by ir, 1H-nmr, 13C-nmr and ms.
