193604-41-0

Upstream product

• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 67199-10-4 methyl N-[2-(5-methoxy-1H-indol-3-yl)ethyl]carbamate 
• 193604-37-4 [2-(1-Benzyl-5-methoxy-1H-indol-3-yl)-ethyl]-carbamic acid methyl ester 
• 193604-38-5 [2-(1-Benzyl-5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-carbamic acid methyl ester 
• 193604-39-6 [2-(1-Benzyl-5-methoxy-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-carbamic acid methyl ester 

Downstream Products

• 193604-42-1 (3aS,8aR)-8-Benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-ol 
• 19573-10-5 (-)-norphysostigmine 
• 193604-44-3 Phenyl-carbamic acid (3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester 
• 193604-43-2 Methyl-carbamic acid (3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester 

Relevant academic research and scientific papers

Total syntheses and anticholinesterase activities of (3aS)-N(8)- norphysostigmine, (3aS)-N(8)-norphenserine, their antipodal isomers, and other N(8)-substituted analogues

N(8)-Benzylesermethole (6) was prepared from 5-methoxytryptamine (1) in five steps. Resolution of compound 6 by dibenzoyl- and ditoluyltartaric acid provided enantiomers (-)- and (+)7. After demethylation, reaction with isocyanates and catalytic debenzyla