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TAS-301, also known as Tivantinib, is a small molecule inhibitor that targets the c-Met receptor tyrosine kinase, which plays a crucial role in cell growth, survival, and angiogenesis. It is a promising pharmaceutical candidate for various applications due to its ability to inhibit smooth muscle cell migration and proliferation, block voltage-independent calcium influx, and downstream PKC signaling.

193620-69-8

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193620-69-8 Usage

Uses

Used in Pharmaceutical Industry:
TAS-301 is used as an inhibitor of smooth muscle cell migration and proliferation for the treatment of various diseases characterized by abnormal cell growth and proliferation. Its ability to block voltage-independent calcium influx and downstream PKC signaling makes it a potential therapeutic agent for conditions involving these pathways.
Used in Cardiovascular Applications:
In the field of cardiovascular medicine, TAS-301 is used to inhibit neointimal thickening after balloon catheter injury to the rat common carotid artery. This application helps in preventing the narrowing of blood vessels, which can lead to various cardiovascular complications.
Used in Cancer Treatment:
TAS-301 is also being explored for its potential use in cancer treatment, particularly in targeting the c-Met receptor tyrosine kinase, which is often overexpressed in various types of cancer. By inhibiting this receptor, TAS-301 may help in controlling tumor growth and progression, making it a valuable tool in the fight against cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 193620-69-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,6,2 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 193620-69:
(8*1)+(7*9)+(6*3)+(5*6)+(4*2)+(3*0)+(2*6)+(1*9)=148
148 % 10 = 8
So 193620-69-8 is a valid CAS Registry Number.

193620-69-8 Well-known Company Product Price

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  • Sigma

  • (T9324)  TAS-301  ≥95% (HPLC), solid

  • 193620-69-8

  • T9324-10MG

  • 1,762.02CNY

  • Detail

193620-69-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[bis(4-methoxyphenyl)methylidene]-1H-indol-2-one

1.2 Other means of identification

Product number -
Other names 3-Bis-(4-methoxphenyl)methylene-2-indolinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:193620-69-8 SDS

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