193635-06-2

Upstream product

• 83860-98-4 (2S,3S)-H-3-MeAzy-OMe 
• 88452-79-3 (2S,3S)-N-para-toluenesulfonyl-3-methylaziridine-2-carboxylic acid 
• 43188-53-0 (2S,3R)-methyl-N-(4-methylphenylsulfonyl)-3-hydroxy-2-aminobutanoate 
• 74481-56-4 methyl (2S,3S)-N-triphenylmethyl-3-methylaziridine-2-carboxylate 
• 43188-65-4 methyl (2S,3S)-3-methyl-1-[(4-methylphenyl)sulfonyl]aziridne-2-carboxylate 

Relevant academic research and scientific papers

Reduction of 2-acylaziridines by samarium(II) iodide. An efficient and regioselective route to β-amino carbonyl compounds

A convenient method for the reduction of 2-acylaziridines, aziridine-2- carboxylates and aziridine-2-carboxamides is described. The reduction of all of the substrates examined was extremely rapid and highly regioselective, giving rise to β-amino carbonyl compounds. This method appears to be general for all of the classes of aziridines mentioned above, and also tolerates a variety of nitrogen protecting groups.