19368-46-8 Usage
Uses
Used in Pharmaceutical Industry:
2-[(2-chloro-4-nitrophenyl)carbamoyl]benzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and functional groups contribute to its potential role in the development of drugs that target specific biological pathways or protein receptors, which is crucial for creating effective treatments for a range of diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-[(2-chloro-4-nitrophenyl)carbamoyl]benzoic acid serves as a valuable compound for research purposes. Its potential reactivity and biological activity make it an interesting subject for further exploration and development, with the aim of discovering new drug candidates or enhancing the properties of existing medications.
Check Digit Verification of cas no
The CAS Registry Mumber 19368-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,3,6 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19368-46:
(7*1)+(6*9)+(5*3)+(4*6)+(3*8)+(2*4)+(1*6)=138
138 % 10 = 8
So 19368-46-8 is a valid CAS Registry Number.
19368-46-8Relevant academic research and scientific papers
Garcia-Barrantes, Pedro M.,Cho, Hyekyung P.,Blobaum, Anna L.,Niswender, Colleen M.,Conn, P. Jeffrey,Lindsley, Craig W.
, p. 1869 - 1872 (2016)
This Letter describes the further lead optimization of the VU0486321 series of mGlu1 positive allosteric modulators (PAMs), focused on addressing the recurrent issue of plasma instability of the phthalimide moiety. Here, we evaluated a number of phthalimide bioisosteres, and ultimately identified isoindolinones as the ideal replacement that effectively address plasma instability, while maintaining acceptable mGlu1 PAM potency, DMPK profile, CNS penetration and mGluR selectivity.
